INTERCEPT Blood System for Platelets


The INTERCEPT Blood System for platelets has been shown to inactivate contaminating parasites in platelet products. Various in vitro studies have demonstrated inhibition of parasite replication following photochemical treatment. The results of these studies are summarized in Table 3.

Table 3: Inactivation Claims - Parasites

Parasites Tested Using
the INTERCEPT Blood System
Extent of Inactivation*
(log10 reduction)
Platelets in
plasma/Additive Solution
in plasma
Plasmodium falciparum** (malaria)
Trypanosoma cruzi (Chagas’ disease)
Leishmania mexicana (metacyclic promastigote stage)
Leishmania major Jish (amastigote stage)
Babesia microti (babesiosis)
* “>” refers to inactivation below the limit of detection of the assay
** intracellular
“-” means not tested

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