INTERCEPT Blood System for Platelets
Pathogen Inactivation Data: Viruses
The INTERCEPT Blood System for platelets has been shown to inactivate a variety of viruses. Of viruses tested to date, only HAV and PPV were resistant to inactivation. The results of these studies are summarized below.
| Viruses Tested Using the INTERCEPT Blood System for Platelets | Extent of Inactivation* (log10 reduction) |
| Enveloped Viruses | |
| HIV-1 (cell-associated)*** | >6.1 |
| HIV-1 (cell-free) | >6.2 |
| Clinical isolate of HIV-1 | >3.4 |
| Clinical isolate of HIV-2 | >2.5 |
| Latent proviral HIV-1 | inactivated to the limit of detection |
| HBV (strain MS-2) | >5.5 |
| HCV (strain Hutchison) | >4.5 |
| HTLV-I (Human T-cell Lymphotropic Virus)*** | 4.7** |
| HTLV-II (Human T-cell Lymphotropic Virus)*** | 5.1** |
| Cell-associated Cytomegalovirus (CMV)*** | >5.9 |
| Bovine Viral Diarrhea Virus (BVDV, model virus for human HCV) | >6.0 |
| Duck Hepatitis B Virus (DHBV, model virus for human HBV) | >6.2 |
| West Nile virus | >6.0 |
| Non-Enveloped Viruses | |
| Bluetongue Virus, type 11 | 6.1 to 6.4 |
| Calicivirus | 1.7 to 2.4 |
| Simian Adenovirus (SV15) | 0.7 to 2.3 |
| * “>” refers to inactivation below the limit of detection of the assay ** inherent low-level background in non-infected indicator cells precludes “>” of HTLV *** intracellular |
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Technical Data Sheets section page 3 of 7 
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Use of the INTERCEPT Blood System in the United States is limited by Federal law to investigational use. If you are a resident of the U.S., please click here.
The information on this site is not country-specific, and may contain information that is outside the approved indications for the country in which you are located. The INTERCEPT Blood System is CE marked for use with platelets and plasma.
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Use of the INTERCEPT Blood System in the United States is limited by Federal law to investigational use. If you are a resident of the U.S., please click here.
The information on this site is not country-specific, and may contain information that is outside the approved indications for the country in which you are located. The INTERCEPT Blood System is CE marked for use with platelets and plasma.
Website design by NetPilot Web Solutions