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INTERCEPT Blood System for Plasma
Pathogen Inactivation Data: Viruses

The INTERCEPT Blood System for plasma has been shown to inactivate a variety of viruses.  Viruses shown to be inactivated are listed below.

Viruses Tested Using the INTERCEPT Blood System for Plasma Extent of Inactivation*
(log10 reduction)
Enveloped Viruses  
HIV-1 (cell-associated)** >6.7
HIV-1 (cell-free) >6.8
HBV (strain MS-2) >4.5
HCV (strain Hutchison) >4.5
HTLV-I (Human T-cell Lymphotropic Virus)** ≥4.5
HTLV-II (Human T-cell Lymphotropic Virus)** >5.7
WNV (West Nile Virus) ≥6.8
SARS-CoV (Human Corona Virus) ≥5.5
BVDV (Bovine Viral Diarrhea Virus, model virus for human HCV) ≥6.0
DHBV (Duck Hepatitis B Virus, model virus for human HBV) 4.4 - 4.5
Non-Enveloped Viruses  
BTV (Bluetongue Virus) 5.1
Human Adenovirus-5 ≥6.9
Parvo (Parvovirus B19) 1.8
* “>” refers to inactivation below the limit of detection of the assay
“≥” refers to inactivation at or below the limit of detection of the assay
** intracellular inoculum

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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Use of the INTERCEPT Blood System in the United States is limited by Federal law to investigational use. If you are a resident of the U.S., please click here.

The information on this site is not country-specific, and may contain information that is outside the approved indications for the country in which you are located. The INTERCEPT Blood System is CE marked for use with platelets and plasma.

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